Abcam, ab313503, Human INHBC ELISA Kit

Size: 1 x 96Tests
Human INHBC ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human INHBC in Human in Cell Culture Media, Biofluids samples.
Key facts
Detection method:Colorimetric,
Sample types:Cell culture supernatant, Plasma, Serum,
Reacts with:Human,
Assay type:Sandwich (quantitative),
Sensitivity:= 0.1 ng/mL,
Assay Platform:Pre-coated microplate (12 x 8 well strips)

Product details:
Human INHBC ELISA kit is an
in vitro
enzyme-linked immunosorbent assay for the quantitative measurement of human INHBC in serum, plasma and cell culture supernatants. This assay employs an antibody specific for human INHBC coated on a 96-well plate.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information--20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
INHBC also known as Inhibin Beta C is a protein known for its role in various cellular processes. It has a molecular mass of approximately 42 kDa. This protein expresses in a variety of tissues including liver testis and ovary. INHBC belongs to the transforming growth factor-beta (TGF-beta) superfamily known for its involvement in cell growth and differentiation.
Biological function summary
INHBC functions as part of the Inhibin/Activin complex that regulates follicle-stimulating hormone (FSH) secretion. Activin which INHBC is a subunit of plays a role in reproductive processes and cellular differentiation. This protein actively participates in modulating processes related to gonadal functions and embryogenesis. Its activity impacts cell proliferation anti-inflammatory responses and wound healing.
Pathways
INHBC interplays within the TGF-beta signaling pathway an important pathway controlling cellular proliferation and differentiation. It relates closely to Inhibin Alpha and Activin A within these pathways. These interactions with related proteins allow it to influence reproductive and cellular growth processes and maintain regulatory balances in physiology.
INHBC correlates with conditions such as reproductive system disorders and certain cancers. Its overexpression or dysregulation can link to ovarian cancer through its association with Activin A. Research suggests that alterations in INHBC levels may influence pathological conditions by disturbing normal growth factor signaling emphasizing its role in disease progression.