Abcam, ab52627, Anti-Notch1 antibody [EP1238Y]

Size: 20µL / 100µL / 1mL
Anti-Notch1 antibody [EP1238Y] (ab52627) is a rabbit monoclonal antibody detecting Notch1 in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IHC-P, ICC/IF . Suitable for Human, Mouse . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 200 publications - Trusted since 2007
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EP1238Y,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Human,
Applications:WB, IHC-P, ICC/IF, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:80% identities with Notch 2 and 81% with Notch 3

Product details:
Notch 1 (encoded by the Notch 1 gene) is a member of the Notch family of receptors. When bound to a ligand, the Notch1 receptor sends signals critical for normal development of many tissues throughout the body. Notch1 signalling supports the determination and specialization of cells as well as playing a role in cell proliferation, differentiation, and apoptosis.
Product Specifications
Anti-Notch1 antibody [EP1238Y] (ab52627) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB in human, mouse samples.
Anti-Notch1 antibody [EP1238Y] (ab52627) specifically detects Notch1 (UniProt ID: P46531; Molecular weight: 271kDa) and is sold in 100 µL and 1 mL selling sizes.
Quality and Validation
Abcam's high quality manufacturing and validation processes ensure Anti-Notch1 antibody [EP1238Y] (ab52627) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
The specificity of Anti-Notch1 antibody [EP1238Y] (ab52627) has been confirmed by testing in knockout samples.
Anti-Notch1 antibody [EP1238Y] (ab52627) has been cited over 201 times in peer reviewed journals and is trusted by the scientific community.
Anti-Notch1 antibody [EP1238Y] (ab52627) has 17 independent reviews from customers.
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Antibody clone EP1238Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, PE, APC, HRP, Alkaline Phosphatase, Alexa Fluor® 488, Alexa Fluor® 594, Alexa Fluor® 555, Alexa Fluor® 750 (
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Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle