Abcam, ab67913, Anti-STYXL1 antibody

Size: 50µg
Mouse Polyclonal STYXL1 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human STYXL1.
Key facts
Host species:Mouse,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Human STYXL1.Q9Y6J8

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4, Shipped at conditions-Blue Ice, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
STYXL1 also known as serine/threonine/tyrosine interacting-like protein 1 and pseudo-phosphatase STYXL1 is a pseudo-phosphatase that lacks enzymatic activity due to alterations in its catalytic domain. Researchers measure its mass around 33 kDa. STYXL1 gets expressed across various tissues showing higher levels in the brain and testes. Unlike typical phosphatases STYXL1 seems to act without catalyzing dephosphorylation reactions.
Biological function summary
STYXL1 functions in regulating cellular processes despite its lack of catalytic activity. STYXL1 is associated with the regulation of cell signaling pathways and may interact with signaling proteins. It plays a role in modulating cellular communication networks by possibly scaffolding interactions rather than direct enzymatic activity. STYXL1 might exist as part of a complex where it collaborates with other proteins to mediate signaling effects.
Pathways
Researchers associate STYXL1 with the ERK/MAPK signaling pathway which controls processes such as cell division and differentiation. In this pathway STYXL1 might interact with kinases like ERK1/2 although it does not act as a traditional signaling enzyme itself. Another important pathway is the apoptosis signaling where STYXL1 impacts cellular decisions of life and death. Its pseudo-phosphatase nature could influence the pathway interactions by binding to components within these networks thereby adjusting signaling output without dephosphorylating substrates.
Scientists link alterations in STYXL1 activity with cancer and neurodegenerative diseases. Abnormal expressions or mutations of STYXL1 may disrupt cell signaling pathways contributing to tumor growth and progression. In neurodegenerative conditions STYXL1 could affect neuronal survival pathways potentially involving proteins like tau where dysregulation impacts cell integrity and function. Understanding STYXL1's role in these disorders can help develop targeted therapeutic strategies.