Abcam, ab69467, FITC Anti-Klebsiella spp antibody

Size: 500µL
Rabbit Polyclonal Klebsiella spp antibody - conjugated to FITC. Suitable for ICC/IF, IHC-Fr and reacts with Klebsiella pneumoniae samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing Klebsiella spp protein.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Conjugation:FITC,
Excitation/Emission:Ex: 495nm, Em: 519nm,
Carrier free:No,
Reacts with:Klebsiella pneumoniae,
Applications:ICC/IF, IHC-FrSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:ab69467 reacts with Klebsiella sp. in bacterial and infected tissue samples.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-Preservative: 0.1% Sodium azideConstituents: PBS, 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Klebsiella spp also known as Klebsiella species refer to a group of non-motile Gram-negative bacteria often present in various environments like soil water and plants. The cells of Klebsiella species possess a polysaccharide capsule that is an important virulence factor contributing to their pathogenic potential by protecting against phagocytosis and antimicrobial substances. They exhibit a rod-shaped morphology with a size measuring approximately 1-2 microns in length. Klebsiella spp commonly colonizes the human gastrointestinal tract and respiratory system where they can coexist without causing harm under normal circumstances.
Biological function summary
This group of bacteria functions as opportunistic pathogens often forming biofilms that contribute to their resilience and pathogenicity. Klebsiella spp play roles in nitrogen cycling as they can fix atmospheric nitrogen into ammonia benefiting their surrounding environments. This ability links them to a multi-enzyme complex facilitating processes important for nitrogen utilization and metabolism. The capsule and lipopolysaccharide layers they produce significantly enhance their survival and capability to cause infections by impeding the immune system.
Pathways
Klebsiella spp are involved in various microbial metabolic pathways notably those associated with nitrogen fixation and carbohydrate metabolism. They participate in denitrification impacting nitrogen availability in the environment and closely interact with other microbial species in these metabolic processes. Klebsiella species share interactions with proteins such as nitrogenase enzymes important for converting atmospheric nitrogen to a biologically usable form emphasizing their role in ecological and host-microbe interactions.
Klebsiella spp are associated with healthcare-associated infections like pneumonia and urinary tract infections. These bacteria frequently cause respiratory infections especially in immunocompromised individuals such as those with chronic lung disease or diabetes. They contribute to diseases by producing extended-spectrum beta-lactamases (ESBLs) enzymes that confer resistance to many beta-lactam antibiotics. Proteins like fimbriae enhance their ability to adhere to host tissues exacerbating their role in opportunistic infections.