Abcam, ab7260, Anti-GFAP antibody - Astrocyte Marker

Size: 50µL
Anti-GFAP antibody (ab7260) is a rabbit polyclonal antibody detecting GFAP in Western Blot, IP, IHC-P, ICC/IF . Suitable for Mouse, Rat . - Over 1200 publications - Trusted since 2002
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat,
Applications:IHC (PFA fixed), IHC-P, IP, ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Human GFAP.P14136,
Specificity:Specifically recognizes mammalian GFAP on western blots and immunocytochemically. Detects a band of 55kDa corresponding to GFAP and also a GFAP derived 48kDa band. Some customers have successfully used ab7260 on Zebrafish lysates; however we have conflicting data to suggest that not all batches will be suitable for work on Zebrafish. For further information, please contact Abcam Scientific Support.

Product details:
Find all reagents to label astrocytes in our "
Astrocytes markers guide
Anti-GFAP antibody (ab7260) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC (PFA fixed), IHC-P, IP and WB.
Anti-GFAP antibody (ab7260) was first used in a scientific publication in 2006 and has been cited over 1203 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in mouse and rat samples is trusted by the scientific community.
Abcam's high quality validation processes ensure Anti-GFAP antibody (ab7260) has high sensitivity and specificity.
Anti-GFAP antibody (ab7260) has 103 independent reviews from customers.
Anti-GFAP antibody (ab7260) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in 50 µL selling sizes.
GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI) and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases.

Properties and Storage Information:
Form-Liquid, Purity-Whole antiserum, Storage buffer-Preservative: 0.03% Sodium azide, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle