Abcam, ab8580, Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade

Size: 50µg
Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) is a rabbit polyclonal antibody detecting Histone H3 in Western Blot, IP, IHC-P, ICC/IF, ChIP, PepArr . Suitable for Cow, Human . - Over 2130 publications - Trusted since 2002
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Cow, Human,
Applications:ChIP, ICC/IF, WB, PepArr, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P, PepArr and WB.
Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) was first used in a scientific publication in 2002 and has been cited over 2135 times in peer reviewed journals. It's performance in ChIP in human, mouse and rat samples is trusted by the scientific community.
Abcam's high quality validation processes ensure Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) has high sensitivity and specificity.
Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) has 92 independent reviews from customers.
Anti-Histone H3 (tri methyl K4) antibody - ChIP Grade (ab8580) specifically detects Histone H3 Tri Methyl-K4 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 50 µg selling sizes.
Top cited antibody for this target with >2000 citations and >60 five star abreviews. Trimethylation of histone H3 (H3K4me3) is a key epigenetic mark that consistently occurs at transcription start sites, promoting higher transcription activity. H3K4me3 is considered a marker and used as a control for gene activation. It plays a crucial role in cell identity during pre-implantation development and in deriving embryonic stem cells from the inner cell mass and trophoblast stem cells from the trophectoderm. Histone H3 lysine 4 trimethylation (H3K4me3) plays a significant role in cancer by regulating gene expression and chromatin structure.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle