Abcam, ab85933, Anti-ZNF574 antibody

Size: 100µg
Rabbit Polyclonal ZNF574 antibody. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human Zinc finger protein 574.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human Zinc finger protein 574. The exact immunogen used to generate this antibody is proprietary information.Q6ZN55

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab85933 was affinity purified using an epitope specific to ZNF574 immobilized on solid support., Storage buffer-pH: 7 - 8Preservative: 0.09% Sodium azideConstituents: Tris citrate/phosphate, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
ZNF574 also known as Zinc Finger Protein 574 functions as a transcription factor. This protein contains zinc finger domains that allow DNA binding which modulates the expression of specific genes. It has a molecular mass of approximately 74 kDa. Human cells mainly express ZNF574 in tissues such as the liver brain and kidneys where it acts within the nucleus to influence gene transcription.
Biological function summary
Zinc Finger Protein 574 regulates gene expression by binding to DNA at specific sites. As a transcription factor it plays a role in controlling developmental and cellular processes. ZNF574 may function as part of a multiprotein complex collaborating with other transcription factors to enhance or suppress gene transcription. By controlling specific genes it contributes to cell differentiation and the maintenance of normal cellular functions.
Pathways
Zinc Finger Protein 574 participates in essential gene regulatory pathways. It influences cellular processes like cell cycle regulation and apoptosis. Through these pathways ZNF574 interacts with proteins such as p53 a known tumor suppressor and components of the Wnt signaling pathway affecting diverse biological activities that maintain cellular health and contribute to organismal development.
Aberrations in ZNF574 have connections to cancers and neurological disorders. Altered expression levels or mutations can disrupt normal cellular functions leading to tumorigenesis or neurodegenerative conditions. Its relationship with proteins like p53 links it further to cancer biology where imbalance in its regulatory functions may promote malignant cell growth.