Abcam, ab92574, Anti-CD90 / Thy1 antibody [EPR3132]

Size: 20µL / 100µL / 1mL
Anti-CD90 / Thy1 antibody [EPR3132] (ab92574) is a rabbit monoclonal antibody detecting CD90 / Thy1 in Western Blot, IHC-P . Suitable for Human . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 60 publications - Trusted since 2010
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR3132,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:This antibody reacts with mouse samples in WB, but does not work on mouse samples in other applications. Rat cross-reactivity has been tested by western blot only.

Product details:
What is this antibody validated in?
Anti-CD90 / Thy1 antibody [EPR3132] (ab92574) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human samples.
What is the molecular weight of CD90 / Thy1?
Anti-CD90 / Thy1 [EPR3132] (ab92574) specifically detects a band for CD90 / Thy1 (UniProt: P04216) at a molecular weight of 18kDa.
Trusted by the scientific community
Anti-CD90 / Thy1 [EPR3132] (ab92574) was first used in a scientific publication in 2010 and has been cited over 60 times in peer-reviewed journals.
Reviewed by scientists
Anti-CD90 / Thy1 [EPR3132] (ab92574) has over 5 independent reviews from customers.
Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl.
Discover our selection of trial-size antibodies
Specificity confirmed
The specificity of Anti-CD90 / Thy1 antibody [EPR3132] (ab92574) has been confirmed by Western blot testing in THY1 Knockout U2OS cell line,
ab262490
Other related products
We have a range of other formats of antibody clone [EPR3132] also available for your convenience: ab92574, Carrier free -
ab181885
, Carrier free -
ab221607
, Alexa Fluor® 555 -
ab307267
, Alexa Fluor® 647 -
ab311183
, Alexa Fluor® 594 -
ab311841
, Alexa Fluor® 568 -
ab313124
, Biotin -
ab323685
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.05% Sodium azideConstituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 0.1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).
Biological function summary
CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.
Pathways
CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvΒ3 and α5Β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.
CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.