Agilent, PL1180-3350, AdvanceBio SEC 130Å, 7.8 x 150 mm, 2.7 µm, LC column

AdvanceBio SEC 130Å, 7.8 x 150 mm, 2.7 µm, LC column. A size exclusion column for efficient aggregate analysis of peptides and small proteins. The resolving range is 0.1-120 kDa.

Specifications:
Brand: AdvanceBio SEC
Hardware: SS
Inner Diameter (ID): 7.8 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 100 Da
Molecular Weight Upper Limit: 120000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 130 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: 0.02% Sodium Azide
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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The AdvanceBio SEC 130Å, 7.8 x 150 mm, 2.7 µm LC column is designed for high-resolution size exclusion chromatography of proteins, antibodies, and biotherapeutics. Engineered with a uniform 2.7 micron particle size and an optimized 130 angstrom pore structure, it enables precise separation and accurate molecular weight analysis of biomolecules under native conditions. The column supports robust and reproducible performance for critical quality assessment tasks, including aggregate and fragment detection or analysis of monoclonal antibodies and protein-based drugs.

This chromatography solution excels in both research and quality control environments, where reliable characterization of molecular size distributions is essential. Its enhanced efficiency and low band broadening make it suitable for high-throughput laboratories aiming to speed up sample analysis without compromising resolution. The column is compatible with a broad range of LC and UHPLC systems, including Agilent’s InfinityLab LC and 1260 Infinity II Bio-inert LC platforms, ensuring seamless integration and optimal data accuracy. For extended workflow capabilities, it is supported by a comprehensive range of AdvanceBio SEC columns with varying pore sizes and column dimensions. This versatile tool empowers biopharmaceutical and life science researchers with reliable, reproducible results in protein and aggregate quantification.