Agilent, PL1180-5325, AdvanceBio SEC 500 Å, 2.7 µm, 7.8 x 300

AdvanceBio SEC 500 Å, 2.7 µm, 7.8 x 300. A size exclusion column for aggregate analysis of large biological molecules such as AAVs, VLPs, and large oligonucleotides.

Specifications:
Brand: AdvanceBio SEC
Guard Column: No
Hardware: SS
Inner Diameter (ID): 7.8 mm
Length: 300 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 5000 Da
Molecular Weight Upper Limit: 5 MDa
Particle Size: 2.7 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 500 Å
Pressure Rating: 400 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer/0.02% Sodium azide
Storage Temp Conditions: Store at ambient temperature
pH Range: 2-8.5

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The AdvanceBio SEC 500 Å column is designed for high-resolution size exclusion chromatography of biomolecules, offering exceptional performance with its 2.7 µm particle size and a 7.8 x 300 mm format. Engineered for precise molecular size determination, it delivers fast and accurate separation of proteins, antibodies, and other biological macromolecules, making it ideal for quality control, aggregation analysis, and purity assessment in biopharmaceutical research.

Featuring a 500 Å pore size, this column is optimized to resolve molecular weights typical of monoclonal antibodies, fragments, and protein complexes. It supports rapid analysis without compromising resolution, enabling high-throughput workflows in pharmaceutical development and characterization laboratories.

This column is compatible with all major liquid chromatography systems including Agilent InfinityLab and other HPLC or UHPLC platforms, ensuring seamless integration into existing workflows. It pairs effectively with Agilent AdvanceBio SEC standards and compatible buffers for robust, reproducible separations.

Trusted by researchers in protein therapeutics and structural biology, the AdvanceBio SEC 500 Å column offers reliable performance for applications ranging from aggregate detection to size-based fractionation. Its durability and consistent reproducibility help streamline method development, enhance analytical confidence, and support regulatory compliance in complex biological analyses.