Agilent, PL1251-1103, PL-SAX 4000Å, 25 x 50 mm, 10 µm

PL-SAX 4000Å, 25 x 50 mm, 10 µm. A strong anion exchange HPLC prep column with fully porous PS/DVB particles. This column can withstand a wide pH range (1-14) and is stable at elevated temperatures

Specifications:
Brand: PL-SAX
Hardware: SS
Inner Diameter (ID): 25 mm
LC Platform: Preparative HPLC
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: OligosProteins
Particle Size: 10 µm
Particle Type: Fully Porous
Phase: SAX
Pore Size: 4000 Å
Pressure Rating: 207 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: 0.1M Sodium Sulfate
Technique: LC
UNSPSC Code: 41115711
pH Range: 1-14

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The PL-SAX 4000Å, 25 x 50 mm, 10 µm is designed for high-resolution anion exchange chromatography, offering robust separation capabilities for biopolymers such as proteins, nucleic acids, and oligonucleotides. Utilizing strong anion exchange chemistry on a rigid, highly porous polymer substrate with a large pore size of 4000 Å, this product delivers excellent performance when analyzing large biomolecules that require minimal mass transfer resistance.

With its 10 µm particle size and a 25 x 50 mm column dimension, this product supports preparative or analytical workflows in academic, pharmaceutical, and biotechnology laboratories. It is ideal for applications such as biomolecule purification, charge variant analysis, and quality control of therapeutic proteins. The large pore structure ensures enhanced recovery and resolution, especially for high-molecular-weight species.

Compatible with a wide range of HPLC and FPLC systems, the column can be used alongside other polymer-based Agilent media, such as PL-SCX or other PL-SAX phases, to tailor separations further. Its stable performance across a broad pH and salt concentration range provides flexibility for method development and scale-up, supporting demanding research and industrial processes.