Agilent, PL1512-1802, PLRP-S 1000Å, 4.6 x 50 mm, 8 µm

PLRP-S 1000Å, 4.6 x 50 mm, 8 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 8 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 1000 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This advanced polymeric reverse phase column features a 1000 angstrom pore size and 8 micron particle size, engineered for robust and reproducible chromatographic performance. With dimensions of 4.6 by 50 millimeters, it is tailored for high-resolution separation of large biomolecules, including peptides, oligonucleotides, proteins, synthetic polymers, and other macromolecules. Its chemically resistant material enables operation across a wide pH range and withstands exposure to aggressive solvents, making it suitable for demanding analytical and preparative workflows.

Typical usage scenarios include method development for biopharmaceutical research, analysis of therapeutic proteins, antibody characterization, and quality control in bioprocessing. The optimized pore structure facilitates efficient mass transfer and minimizes sample interaction with the stationary phase, ensuring sharp peak shapes for high molecular weight analytes. This column seamlessly integrates with most standard HPLC systems, including Agilent and compatible third-party platforms, and is often paired with other Agilent PLRP-S columns of different pore sizes for method scaling and optimization.

Researchers benefit from its durability, reproducibility, and versatile performance, supporting routine analysis as well as complex separations in pharmaceutical, academic, and industrial laboratories. Accessories and guard columns designed for the PLRP-S product line further enhance sample protection and column longevity.