Agilent, PL1512-5801, PLRP-S 300Å, 4.6 x 250 mm, 8 µm

PLRP-S 300Å, 4.6 x 250 mm, 8 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 8 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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The PLRP-S reversed-phase column features a highly crosslinked polystyrene-divinylbenzene (PS-DVB) matrix with 300 angstrom pore size, measuring 4.6 mm in internal diameter and 250 mm in length, with an 8 micron particle size. This column is engineered for robust analysis and purification of large biomolecules such as peptides, proteins, and oligonucleotides. The rigid polymeric structure provides exceptional mechanical stability and wide pH compatibility (1–14), enabling operation under harsh conditions and suitability for method development where both acidic and basic mobile phases are used.

Optimized for high-resolution separations, this column is extensively used in proteomics research, pharmaceutical development, and quality control laboratories. Its non-silica base eliminates silanol activity, reducing non-specific interactions and enhancing reproducibility. The large pore size supports effective separation of high-molecular-weight samples, making it ideal for biomolecule characterization and fractionation.

Compatible with a wide range of HPLC and UHPLC systems, including Agilent 1100, 1200, and Infinity Series, the column integrates seamlessly into existing workflows. Related products include other pore sizes and dimensions within the PLRP-S line, supporting diverse application needs. This column delivers consistent performance and longevity, making it a reliable choice for demanding bioanalytical applications.