Biolegend, 131712, APC anti-mouse CD96 (TACTILE) Antibody, 100μg

CD96, also called Tactile is preferentially expressed on T cells and NK cells and may play a role in the adhesive interaction of activated T and NK cells to their target cells during late phase of immune response. It may also plays a role in antigen presentation and/or lymphocyte activation.
100μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
Product Citations: Saha S, et al. 2023. Sci Rep. 13:4609. PubMed Li N, et al. 2019. Curr Protoc Toxicol. e74:80. PubMed Yang J, et al. 2024. Cancer Immunol Res. 575:12. PubMed
RRID: AB_2650740 (BioLegend Cat. No. 131711) AB_2650741 (BioLegend Cat. No. 131712)
Structure: Type 1 single chain membrane glycoprotein of 569 amino acids. Member of the Ig superfamily with three Ig domains and extensive glycosylation.
Distribution: Positive on most peripheral T cells, NK cells and upregulated when activated.
Ligand/Receptor: CD155, nectin 1
Cell Type: NK cells, T cells
Biology Area: Immunology, Inhibitory Molecules
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Wang PL, et al. 1992. J Immunol. 148:2600-8.
Gene ID: 84544
UniProt: View information about CD96 on UniProt.org
Clone: 3.3
Regulatory Status: RUO
Other Names: Tactile (T cell-activated increased late expression)
Isotype: Rat IgG1, κ