Biolegend, 158902, Purified anti-mouse LIFR Antibody, 500μg

Leukemia inhibitory factor (LIFR) receptor alpha belongs to the type I cytokine receptor family, combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of LIF, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in theadult and the embryo.
500μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant mouse LIFR
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: W16163A can be used for surface staining of LIFR expressed on mouse splenocytes and bone marrow cells (tested on C57BL/6).
RRID: AB_2876550 (BioLegend Cat. No. 158902)
Distribution: IFNAR+ pDCs, IFNAR+ lymphocytes, and Ly6C+ lymphocytes. Dim expression by CD11b+ and CD90.2+ lymphocytes.
Ligand/Receptor: LIFR combines with gp130 to form a receptor complex that mediates the action of LIF
Cell Type: Macrophages, Monocytes
Molecular Family: Cytokine/Chemokine Receptors
Antigen References: Wang T, et al. 2019. Mol Med Rep. 19:4719-26. Cheng L, et al. 1994. Development. 120:3145-3513. Mikelonis D, et al. 2014. Orphanet Journal of Rare Diseases. 9:34.
Gene ID: 16880
UniProt: View information about LIFR on UniProt.org
Clone: W16163A
Regulatory Status: RUO
Other Names: Leukemia inhibitory factor receptor alpha, Leukemia inhibitory factor receptor, Lifr, LIFR-a
Isotype: Rat IgG2b, κ