Product Description
The I-A d MHC class II alloantigen is expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2 d bearing mouse strains. It is involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.
100μg
Verified Reactivity: Mouse
Antibody Type: Recombinant
Host Species: Mouse
Formulation: 150 mM sodium chloride & 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.06 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Does not cross-react with other haplotypes (e.g., a, b, k, p, q, s).
RRID: AB_3675021 (BioLegend Cat. No. 166902)
Structure: MHC class II
Distribution: Expressed on B cell and activated T cells, antigen presenting cells of H-2d mice
Function: Antigen presentation
Ligand/Receptor: CD3/TCR, CD4
Cell Type: Antigen-presenting cells, B cells, T cells, Tregs
Biology Area: Immunology, Innate Immunity
Molecular Family: MHC Antigens
Antigen References: Watts C. 1997. Annu Rev Immunol. 15:821-50.
Gene ID: 14961
Clone: 39-10-8.RecM1
Regulatory Status: RUO
Other Names: MHC class II
Isotype: Mouse IgG1, κ
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Collaboration
Tony Tang
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