Biolegend, 313903, FITC anti-human CD6 Antibody, 25tests

CD6 is a 100-130 kD single chain transmembrane glycoprotein also known as T12. It is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6, interacting with its ligand CD166 (also known as ALCAM), is involved in T cell development and activation, as well as thymocyte adhesion.
25tests
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)
Product Citations: Schmidt J, et al. 2021. Cell Rep Med. 100194:2. PubMed Ruth JH, et al. 2021. JCI Insight. 6:e145662. PubMed
RRID: AB_2076599 (BioLegend Cat. No. 313904)
Structure: Scavenger receptor superfamily, single chain transmembrane glycoprotein, 100-130 kD
Distribution: T cell and B cell subset, thymocytes
Ligand/Receptor: CD166 (ALCAM)
Cell Type: T cells, B cells, Thymocytes
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: 1. Aruffo A, et al. 1997. Immunol. Today 18:498.
Gene ID: 923
UniProt: View information about CD6 on UniProt.org
Clone: BL-CD6
Regulatory Status: RUO
Other Names: T12
Isotype: Mouse IgG1, κ