Biolegend, 334401, Purified anti-human CD245 (p220/240) Antibody, 25μg

CD245 is a 220-250 kD transmembrane glycoprotein, also known as p220/240, DY12 or DY35. It is expressed on peripheral blood lymphocytes, monocytes, granulocytes, and platelets. The expression level of CD245 on lymphocytes can be upregulated after 3-7 days stimulation with PHA. It has been reported that CD245 is involved in signal transduction and costimulation of T and NK cells.
25μg
Verified Reactivity: Human
Reported Reactivity: African Green, Baboon, Cynomolgus
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_1186022 (BioLegend Cat. No. 334402)
Distribution: Blood lymphocytes, monocytes and granulocytes
Function: Signal transduction and costimulation
Cell Type: Granulocytes, Lymphocytes, Monocytes
Biology Area: Immunology
Molecular Family: CD Molecules
Antigen References: 1. H. Zola et al. Eds. 2007. Leukocyte and Stromal Cell Molecule:The CD Markers. WILEY-LISS:A John Wiley & Sons Inc, Publication
Gene ID: 4863
UniProt: View information about CD245 on UniProt.org
Clone: DY12
Regulatory Status: RUO
Other Names: P220/240, DY12, DY35
Isotype: Mouse IgG1, κ