Biolegend, 336107, PE anti-human CD93 Antibody, 25tests

CD93 is a 110 kD O-sialoglycoprotein, known as complement C1q receptor, C1qR1, C1qRp (C1q receptor precursor), or GR11. It is expression on monocytes, granulocytes, platelets, and endothelial cells. CD93 regulates phagocytosis of apoptosis cells, and leukocyte-endothelial cell adhesion.
25tests
Verified Reactivity: Human
Reported Reactivity: African Green, Baboon, Cynomolgus, Rhesus
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References(PubMed link indicates BioLegend citation): Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
Product Citations: Houtsma R, et al. 2021. STAR Protoc. 2:100864. PubMed Derer S, et al. 2015. J Immunol. 195: 5077 - 5087. PubMed Antonyshyn JA, et al. 2021. Commun Biol. 4:1205. PubMed
RRID: AB_2076049 (BioLegend Cat. No. 336107) AB_2076048 (BioLegend Cat. No. 336108)
Structure: 110 kD glycoprotein
Distribution: Monocytes/macrophages, granulocytes, platelets, endothelial cells
Function: C1q receptor, predicted to assist phagocytosis
Ligand/Receptor: Complement C1q
Cell Type: Endothelial cells, Granulocytes, Macrophages, Monocytes, Platelets
Biology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: CD Molecules
Antigen References: 1. Zola H et al. ed. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication 2. Nepomuceno RR, et al. 1998. J. Immunol. 160:1929
Gene ID: 22918
UniProt: View information about CD93 on UniProt.org
Clone: VIMD2
Regulatory Status: RUO
Workshop: VI MR8
Other Names: GR11, C1qRp, C1qR1, CDw93
Isotype: Mouse IgG1, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.