Biolegend, 366008, APC anti-human CD105 (Endoglin) Recombinant Antibody, 100tests

Endoglin (CD105) is a type I membrane glycoprotein that is part of the TGF beta receptor complex. It is expressed in vascular endothelial tissue as well as a variety of other tissues. Endoglin may also be involved in the cytoskeletal organization affecting cell morphology and migration.
100tests
Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Immunogen: EDG (CD105) isolated from acute lymphoblastic leukemia cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool).
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Red Laser (633 nm)
RRID: AB_3720590 (BioLegend Cat. No. 366007) AB_3720590 (BioLegend Cat. No. 366008)
Cell Type: Endothelial cells, Hematopoietic stem and progenitors, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area: Angiogenesis, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: Li C, et al. 2003. Br J Cancer. 88:1424. Sanz-Rodriguez F, et al. 2004. J Biol Chem. 279(31):32858-68. Takahashi N, et al. 2001. Clin Cancer Res. 7(3):524-32. Seon BK, et al. 1997. Clin Cancer Res. 3(7):1031-44. Haruta Y & Seon BK. 1986. Proc Natl Acad Sci U S A. 83: 7898-902.
Gene ID: 2022
UniProt: View information about CD105 on UniProt.org
Clone: QA19A14
Regulatory Status: RUO
Other Names: Endoglin, Cell surface MJ7/18 antigen, END, Edg, ENG, HHT1, ORW1
Isotype: Mouse IgG1, κ