Biolegend, 447104, ELISA MAX™ Deluxe Set Mouse IL-25 (IL-17E), 5plates

IL-25, also known as IL-17E, is a pro-inflammatory cytokine encoded by the IL25 gene located on chromosome 14. The IL-17 family consists of IL-17A, IL-17B, IL-17C, IL-17F, IL-17A/F, and IL-17E. The IL-17 family has a similar protein structure with four conserved cysteine residues and two disulfide bonds. IL-25 expression is widely distributed and can be produced by a variety of cells and tissues. IL-25 induces T helper 2 (Th2) expansion and production of cytokines IL-4, IL-5, and IL-13. This is important in eosinophil expansion, regulating gut immunity, and in the response to helminth parasites. IL-25 has been demonstrated to play a role in allergy and asthma. IL-25 levels are positively correlated with the severity of allergenic rhinitis in patients. Blocking IL-25 has been proposed as an allergy treatment in combination with other therapies. IL-25 has also been associated with the pathogenesis of rheumatoid arthritis and is frequently upregulated in the serum and synovial fluid of patients and in mouse models of rheumatoid arthritis. BioLegend's ELISA MAX™ Mouse IL-25 (IL-17E) ELISA MAX™ Deluxe Set is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate. The plate is pre-coated with a monoclonal mouse capture antibody. The detection antibody is a biotinylated mouse monoclonal antibody. This kit is specifically designed for the accurate quantitation of mouse IL-25 from cell culture supernatant, serum, plasma and other biological fluids. It is analytically validated with ready-to-use reagents.
5plates
Verified Reactivity: Mouse
Application: ELISA
Sensitivity: 1.31 ± 0.43 pg/mL
Standard Range: 12.5 - 800 pg/mL
Cell Type: Basophils, Dendritic cells, Eosinophils, Epithelial cells, Macrophages, Mast cells, T cells
Biology Area: Adaptive Immunity, Immuno-Oncology, Immunology
Molecular Family: Cytokines/Chemokines
Gene ID: NA
UniProt: View information about IL-25 on UniProt.org
Regulatory Status: RUO
Other Names: IL25, IL-17E, IL17E, Interleukin 25, Interleukin 17E
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.