Biolegend, 448704, ELISA MAX™ Deluxe Set Human Amyloid Beta (1-42), 5plates

The Amyloid peptides are peptides of 36-43 amino acids which are produced through the post-translational cleavage of the Amyloid Precursor Protein by beta and gamma secretase. Although numerous different Amyloid-Beta species exist, the majority of the Amyloid-Beta peptides produced by post-translational modification consists of either Amyloid-Beta (1-40) (80-90%) and Amyloid-Beta (1-42) (5-10%). Both variants are major components of the extracellular plaques found in Alzheimer’s brain. However, Amyloid-Beta (1-42) is reported to be more prone to aggregation than the (1-40) variant despite differing in only 2 amino acids at the C terminus. Other studies that aimed at characterizing the difference in aggregation tendency between the two variants suggested that they have distinct 3D structures in solution. BioLegend’s ELISA MAX™ Deluxe Set is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA). The kit contains a monoclonal capture antibody and biotinylated monoclonal antibody specific for human Amyloid-Beta (1-42). This kit is specifically designed for the accurate quantitation of human Amyloid-Beta (1-42) in cerebrospinal fluid, serum and plasma. BioLegend’s ELISA MAX™ Deluxe Sets are sensitive, accurate, and robust.
5plates
Verified Reactivity: Human
Application: ELISA
Sensitivity: 0.718 ± 0.190 pg/mL
Standard Range: 3.125 - 200 pg/mL
Cell Type: Neural Stem Cells, Neurons
Biology Area: Cell Death, Neurodegeneration, Neuroscience, Neuroscience Cell Markers, Protein Misfolding and Aggregation
Molecular Family: APP/β-Amyloid, APP/Aβ Degradation
Gene ID: NA
UniProt: View information about Amyloid Beta 1-42 on UniProt.org
Regulatory Status: RUO
Other Names: Human Aβ42, Amyloid-beta protein 42
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.