Biolegend, 448904, ELISA MAX™ Deluxe Set Human Properdin, 5plates

Properdin, known as CFP or complement factor P, is a protein that activates the complement regulatory proteins of the innate immune system. It is a glycoprotein produced by leukocytes and found in plasma. It positively regulates alternative pathway activity by stabilizing C3 and C5 convertases. Properdin’s involvement in complement activity changes the cellular microenvironment, therefore contributing to both the innate and adaptive immune response. This includes production of inflammatory cytokines, immune cell infiltration, antigen presenting cell maturation and tissue damage. As an inflammatory modulator, it can enhance damaging inflammation. Studies have shown its implication in several renal diseases, highlighting its role as a potential urinary biomarker. Its role in inflammatory conditions is multifaceted and as such, there is potential for the development of new disease therapies. Biolegend’s ELISA MAX™ Deluxe Set Human Properdin ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA), utilizing a monoclonal capture antibody and biotinylated monoclonal antibody specific for human Properdin. This set contains necessary reagents for the accurate quantification of natural and recombinant human Properdin in serum, plasma, urine and other biological fluids. Biolegend’s ELISA MAX™ Deluxe Sets are cost-effective, sensitive, accurate, and robust.
5plates
Verified Reactivity: Human
Application: ELISA
Sensitivity: 7.21 pg/mL
Standard Range: 23.44 - 1500 pg/mL
Molecular Family: Scaffold Proteins
Gene ID: NA
UniProt: View information about Properdin on UniProt.org
Regulatory Status: RUO
Other Names: CFP, Complement Factor P
Q: Do the ELISA MAX™ Deluxe Sets come with plates?
A: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.