Biolegend, 610202, Purified anti-DEPTOR Antibody, 100μg

DEPTOR/DEPDC6, found only in vertebrates, plays an important role in multiple cellular processes such as cell growth, autophagy, apoptosis, ER stress and adipogenesis. It inbibits mTORC1 and mTORC2 kinase activity through direct interaction with mTOR in these complexes. DEPTOR also associates with chromatin and may regulate transcription, and can act as either an oncogene or oncosuppressor depending on cell- or tissue-specific context.
100μg
Verified Reactivity: Human, Mouse, Rat, Hamster
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant Human DEPTOR Protein (1-219 a.a.)
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2783359 (BioLegend Cat. No. 610201) AB_2783360 (BioLegend Cat. No. 610202)
Distribution: Cytoplasm/ Nucleus, A little bit more in Cytoplasm
Biology Area: Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Chromatin Remodeling/Epigenetics, Signal Transduction, Transcription Factors
Molecular Family: Tumor Suppressors
Gene ID: 64798
UniProt: View information about DEPTOR on UniProt.org
Clone: W17128A
Regulatory Status: RUO
Other Names: DEPTOR, DEPDC6
Isotype: Rat IgG2b, κ