Biolegend, 644002, Purified anti-Cyclin A Antibody, 100μg

Cyclins regulate the activity of the Cyclin-dependent protein kinases. Cyclin A is involved in the regulation of the cell cycle and seems to be essiential for S phase and M phase. Studies have shown that overexpression of cyclin A can accelerate the G1 to S phase. Cyclin A is a marker for actively proliferating cells and for cells in S phase.
100μg
Verified Reactivity: Human, Mouse
Reported Reactivity: Cow
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Cyclin A fusion protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested ICFC - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5-1 µg per ml antibody dilution buffer. For intracellular flow cytometric staining, the suggested use of this reagent is ≤ 1 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Product Citations: Danno S, et al. 2017. Genes Cells. 22:220. PubMed
RRID: AB_2071969 (BioLegend Cat. No. 644001)
Distribution: 55 kd protein
Biology Area: Cell Biology, Cell Cycle/DNA Replication
Antigen References: 1. Pagano M et al. 1992. EMBO J 11:961 2. Geley S et al. 2001 J Cell Biol. 153:137 3. Resinitzky D et al. 1995. Mol Cell Biol 15:4347 4. Furuno N et al. 1999. J Cell Biol. 147:295
Gene ID: 890
UniProt: View information about Cyclin A on UniProt.org
Clone: E23.1
Regulatory Status: RUO
Other Names: CCNA2, cyclin A2, CCN1, CCNA
Isotype: Mouse IgG2a, κ