Biolegend, 665903, Purified anti-Shiga toxin Stx2A Antibody, 25μg

The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subnit is cleaved by furin in two fragments: A1, the catalytically active fragment, and A2, the fragment that is essential for holotoxin assembly with the B subunits.
25μg
Verified Reactivity: E. coli
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Peptide
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1:500-1:2500 diluted (0.2 - 1.0 µg/mL). It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Clone 1C6A6G9 recognizes epitope 198-212 (REFRQALSETAPVYT).
RRID: AB_2721751 (BioLegend Cat. No. 665903) AB_2721750 (BioLegend Cat. No. 665904)
Structure: A is a 35 kD subunit of Shiga toxin.
Biology Area: Bacterial proteins and Toxins, Cell Biology
Gene ID: 1262249
UniProt: View information about Stx2A on UniProt.org
Clone: 1C6A6G9
Regulatory Status: RUO
Other Names: SLT-2 A subunit, SLT-2a, SLT-IIa, Verocytotoxin 2 subunit A, Verotoxin 2 subunit A, rRNA N-glycosidase 2, stxA2, stx2A
Isotype: Mouse IgG1, κ