Biolegend, 666501, Purified anti-ATF1 Antibody, 25μg

ATF1 is a transcription factor regulated by multiple signaling pathways. For example, ERK1/2 and p38 MAPK could phosphorylate and activate ATF1. Activated ATF1  could then regulate downstream targets to mediate cell growth and proliferation. Chimeric proteins of ATF1 fused with FUS or EWSR1 have been discovered in angiomatoid fibrous histiocytoma and clear cell sarcoma.
25μg
Verified Reactivity: Human, Mouse, Rat
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Human recombinant Full length ATF1 Protein expressed in E. Coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2810696 (BioLegend Cat. No. 666501) AB_2810697 (BioLegend Cat. No. 666502)
Distribution: Nucleus
Function: Transcription factor
Biology Area: Cell Biology, Cell Proliferation and Viability, Signal Transduction, Transcription Factors
Molecular Family: Nuclear Markers
Gene ID: 466
UniProt: View information about ATF1 on UniProt.org
Clone: W16033B
Regulatory Status: RUO
Other Names: ATF1, TREB36
Isotype: Rat IgG2a, λ