Product Description
FMIP, also known as FMS-Interacting Protein and THOC5, is a member of the THO complex, which is part of the larger TREX (transcription/export) complex. The TREX complex binds specifically to spliced mRNA, where it binds upstream of the exon-junction complex and aids in mRNA export. TREX machinery is also utilized by Kaposi’s sarcoma-associated herpesvirus and certain other viruses for the propagation of virus production. FMIP may also be involved in granulocyte and adipocyte differentiation.
100microl
Verified Reactivity: Human, Mouse, Rat, Hamster
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: This monoclonal antibody was raised against a bacterially expressed C-terminal recombinant GST fusion protein derived from 3' 2.25 kb EcoRV-EcoR1 FMIP cDNA fragment.
Formulation: Phosphate-buffered solution.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 1 mg/ml
Storage & Handling: This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2564966 (BioLegend Cat. No. 833401)
Structure: Expected MW: 89 kD
Biology Area: Cell Biology, Neuroinflammation, Neuroscience
Gene ID: 8563
UniProt: View information about FMIP on UniProt.org
Clone: F6D/11
Regulatory Status: RUO
Other Names: THOC5, C22orf19, PK1.3, fSAP79, hTREX90, THO complex subunit 5 homolog, PP39.2, hTREX90, placental protein 39.2, Fms-interacting protein, NF2/meningioma region protein pK1.3, functional spliceosome-associated protein 79
Previously: Covance Catalog# MMS-5281
Isotype: Mouse IgG1, κ
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Collaboration
Tony Tang
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