Biolegend, 860001, Purified anti-Lysozyme Antibody, 25μg

Lysozyme is an antimicrobial enzyme  that is abundantly present in secretions such as tears, saliva and mucus. Its hydrolase activity leads to the breakdown of the gram-positive bacterial cell wall and lysis of the bacteria.
25μg
Verified Reactivity: Human, Mouse, Rat
Antibody Type: Polyclonal
Host Species: Rabbit
Immunogen: Recombinant Lysozyme expressed in E.coli.
Formulation: 0.01 M PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Application: WB - Quality testedIHC-P - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 µg per ml for human, and 1.0 - 2.0 µg per ml for mouse and rat. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2810736 (BioLegend Cat. No. 860001)
Structure: Lysozyme is a 148 amino acid protein with an apparent molecular mass of ~ 16kD.
Distribution: Tissue Distribution: Spleen, kidney, milk, tears, and plasma Cellular Distribution: Cytosol
Function: Lysozyme is expressed in many immune cells including monocytes and macrophages. It plays an important role in innate immunity by hydrolyzing peptidoglycans found in bacterial cell wall and thus destroying the bacteria.
Interaction: Bacterial peptidoglycan
Cell Type: Macrophages, Mesenchymal cells, Monocytes, Neutrophils
Biology Area: Bacterial proteins and Toxins, Cell Biology, Immunology, Innate Immunity
Molecular Family: Enzymes and Regulators, Innate Immune Signaling, Proteases
Antigen References: Mallamace D, et al. 2018. Int J Mol Sci. 19(12): E3825. Delorme-Axford E and Klionsky DJ. 2018. Autophagy. 14(3):365.
Gene ID: 40681711025211
UniProt: View information about Lysozyme on UniProt.org
Clone: Poly28600
Regulatory Status: RUO
Other Names: Lysozyme, LZM, 1,4-Beta-N-Acetylmuramidase C, EC 3.2.1.17, Lysozyme C, Lysozyme (Renal Amyloidosis) 2
Isotype: Rabbit Polyclonal IgG