Biolegend, 871601, Purified anti-CD304 (Neuropilin 1) Antibody, 25μg

CD304 (Neuropilin 1) is a membrane receptor that plays a role in establishment of certain neuronal circuits during neurogenesis, as well as in  organogenesis outside of the nervous system. CD304 binds semaphorin 3A and VEGFA. The interaction between CD304 and VEGFA initiates a signaling pathway that is needed for cell migration and axonal guidance in the motor neuron system.
25μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 5.0 - 10 µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2861111 (BioLegend Cat. No. 871601) AB_2861112 (BioLegend Cat. No. 871602)
Structure: CD304 is a 923 amino acid protein with predicted molecular mass of ~103 kD and observed molecular mass at ~ 120 kD.
Distribution: Tissue Distribution: Ubiquitously expressed Cellular Distribution: Plasma membrane, extracellular, cytosol, cytoskeleton, endosome
Function: CD304 is involved in signaling that is needed for cell migration and axonal guidance.
Ligand/Receptor: Semaphorin 3A, VEGFA
Cell Type: Endothelial cells
Biology Area: Angiogenesis, Neurodegeneration, Neuroscience, Neuroscience Cell Markers
Molecular Family: Semaphorin Receptors
Antigen References: Niland S, Eble JA. 2019. Int. J. Mol. Sci. 20(3). Gudapati P, et al. 2020. Cytometry B. Clin. Cytom. 10.1002/cyto.b.21866. Ding Z, et al. 2019. Mol. Carcinog. 58:1019.
Gene ID: 8829
UniProt: View information about CD304 on UniProt.org
Clone: A18190A
Regulatory Status: RUO
Other Names: Vascular Endothelial Cell Growth Factor 165 Receptor, Neuropilin-1
Isotype: Mouse IgG2a, κ