Biolegend, 914204, Purified anti-Pan-Cytokeratin Antibody, 100μg

AE-1 immunoreacts with an antigenic determinant present on most of the subfamily A cytokeratins, including cytokeratins with molecular weights of 56.5, 50, 48 and 40 kD. AE-3 reacts with an antigenic determinant shared by the subfamily B cytokeratins including cytokeratins with molecular weights of of 64, 59, 58, 56, and 52 kD.
100μg
Verified Reactivity: Human, Rat
Reported Reactivity: Dog, Non-Human Primate
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: This antibody was developed using human epidermal keratins.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: IHC-P - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 5.0 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
Product Citations: Tiago M, et al. 2020. Br J Cancer. 122:789. PubMed Metcalf KJ, et al. 2022. Matrix Biol Plus. 14:100105. PubMed Jiang S, et al. 2022. Immunity. 55:1118. PubMed Kou R, et al. 2018. Oncol Rep. 7:2013. PubMed Xie S, et al. 2020. Ann Transl Med. 1.384027778. PubMed Chang TH, et al. 2020. Cell Death Dis. 11:338. PubMed Kennedy-Darling J, et al. 2021. Eur J Immunol. 51:1262. PubMed Cai S, et al. 2022. iScience. 25:104980. PubMed
RRID: AB_2616960 (BioLegend Cat. No. 914204)
Biology Area: Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
Molecular Family: Intermediate Filaments
Gene ID: NA
UniProt: View information about Pan-Cytokeratin on UniProt.org
Clone: AE-1/AE-3
Regulatory Status: RUO
Other Names: Pan-Cytokeratin (AE-1/AE-3), AE1/AE3
Isotype: Mouse IgG1, κ