Biolegend, 984404, PE/Cyanine7 anti-human CD154, 500microl

CD154 is the ligand for CD40 (CD40L), also know as gp39, TRAP and T-BAM. It is a 32-39 kD type II transmembrane glycoprotein, belonging to the TNF superfamily. CD154 is expressed on activated T cells. It is important for B cell co-stimulation following binding to its receptor, CD40. Additionally, binding of CD154 to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD154 is also involved in the regulation of cytokine production by T cells.
500microl
Reactivity: Human
Formulation: Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% (w/v) BSA (origin USA), True-Stain Monocyte Blocker™, and a stabilizer.
Preparation: The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration: 100 µg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: Suggested for Flow Cytometry
Disclaimer: WARNINGS AND PRECAUTIONS Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet. This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal. All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations. Do not use this reagent beyond the expiration date stated on the label. Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration. Avoid prolonged exposure of the reagent or stained cells to light.
Antigen References: Gauchat JF, et al. 1993. FEBS Lett. 315:259-66. Hollenbaugh D, et al. 1992. EMBO J. 11:4313-21. Parker DC. 1993. Annu Rev Immunol. 11:331-60.
Clone: 24-31
Other Names: CD40L, gp39, TRAP, T-BAM, TNFSF5
Isotype: Mouse IgG1, κ