Product Description
Size: 20ul / 150ul
The Uteroglobin/CC10 (10490-1-AP) by Proteintech is a Polyclonal antibody targeting Uteroglobin/CC10 in IHC, IF-P, FC (Intra), ELISA applications with reactivity to human, mouse, rat samples
10490-1-AP targets Uteroglobin/CC10 in WB, IHC, IF-P, FC (Intra), IP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive IHC detected in: mouse lung tissue, human lung cancer tissue, rat lung tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF-P detected in: mouse lung tissue
Positive FC (Intra) detected in: A549 cells
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:2000-1:8000
Immunofluorescence (IF)-P: IF-P : 1:50-1:500
Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
Background Information
Uteroglobin, also known as CC10, is a member of the secretoglobin family of small secreted proteins. It is produced by the nonciliated, nonmucous, secretory epithelial clara cells of the pulmonary airways, was first identified in lung lavage by Singh and colleagues. It has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse, bovine
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag0758 Product name: Recombinant human Uteroglobin protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-91 aa of BC004481 Sequence: MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN Predict reactive species
Full Name: secretoglobin, family 1A, member 1 (uteroglobin)
Calculated Molecular Weight: 10 kDa
GenBank Accession Number: BC004481
Gene Symbol: Uteroglobin
Gene ID (NCBI): 7356
RRID: AB_2183285
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P11684
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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