Proteintech, 11212-1-AP, CCNL2 Polyclonal antibody

Size: 20ul / 150ul The CCNL2 (11212-1-AP) by Proteintech is a Polyclonal antibody targeting CCNL2 in WB, ELISA applications with reactivity to human, mouse, rat samples 11212-1-AP targets CCNL2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: A375 cells, HeLa cells, U-251 cells, human placenta tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information CCNL2 (Cyclin-L2) is also named as SB138 and Paneth cell-enhanced expression protein. Human cyclin L2 is a novel member of the cyclin family. Human cyclin L2 shares significant homology to cyclin L1, K, T1, T2, and C, which are involved in transcriptional regulation via phosphorylation of the C-terminal domain of RNA polymerase II (PMID: 14684736). Cyclin L2 co-localizes with splicing factors SC-35 and 9G8 within nuclear speckles and that it associates with hyperphosphorylated, but not hypophosphorylated, RNA polymerase II and CDK p110 PITSLRE kinase via its N-terminal cyclin domains (PMID: 14684736). Human cyclin L2 is expressed ubiquitously in normal human tissues and tumor cells. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag1710 Product name: Recombinant human CCNL2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-220 aa of BC016333 Sequence: MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDSDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSW Predict reactive species Full Name: cyclin L2 Calculated Molecular Weight: 58 kDa Observed Molecular Weight: 28 kDa GenBank Accession Number: BC016333 Gene Symbol: CCNL2 Gene ID (NCBI): 81669 RRID: AB_2073623 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96S94 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.