Proteintech, 11618-1-AP, PRRG2 Polyclonal antibody

Size: 20ul / 150ul The PRRG2 (11618-1-AP) by Proteintech is a Polyclonal antibody targeting PRRG2 in WB, ELISA applications with reactivity to human, mouse, rat samples 11618-1-AP targets PRRG2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse kidney tissue Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information Proline-rich Gla protein 2 (PRRG2) represents one of the four known transmembrane-carboxyglutamic acid proteins in vertebrates. As a founding member of the vitamin K-dependent, single-pass integral membrane protein family, PRRG2 is characterized by an extracellular N-terminus consisting of approximately 45 amino acids rich in Gla, as well as a conserved Pro/Leu-Pro-xaa-Tyr (PY) motif proximal to its C-terminus. PRRG2 primarily localizes to the cell surface, where the Gla domain is exposed extracellularly, serving as a pivotal gene node with positive autoregulatory function that plays a critical role in maintaining human hemostasis (PMID: 38227081). The calculated molecular weight of PRRG2 is usually approximately 22 kda. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag2197 Product name: Recombinant human PRRG2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-179 aa of BC026032 Sequence: MSLGPEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTCGILLIVLAGLGAFWYLRWRQHRGQQPCPQEAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYTSLRRPH Predict reactive species Full Name: proline rich Gla (G-carboxyglutamic acid) 2 Calculated Molecular Weight: 179 aa, 20 kDa Observed Molecular Weight: 16-22 kDa GenBank Accession Number: BC026032 Gene Symbol: PRRG2 Gene ID (NCBI): 5639 RRID: AB_2171684 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O14669 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.