Proteintech, 11982-1-AP, ROBO3 Polyclonal antibody

Size: 20ul / 150ul The ROBO3 (11982-1-AP) by Proteintech is a Polyclonal antibody targeting ROBO3 in WB, ELISA applications with reactivity to human, mouse samples 11982-1-AP targets ROBO3 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Neuro-2a cells, SH-SY5Y cells, Y79 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information ROBO3 belongs to the immunoglobulin superfamily and ROBO family. ROBO3 is thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal cord development, it plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1. It is required for hindbrain axon midline crossing. Defects in ROBO3 are a cause of familial horizontal gaze palsy with progressive scoliosis (HGPPS). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag2608 Product name: Recombinant human ROBO3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-147 aa of BC008623 Sequence: MTPPLQGPRARFRKKPKALPYRRENSPGDLPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKAVQAVPLAAQRVLHPDEEAWLPYSRPSFLSRGQGTSTCSTAGSNSSRGSSSSRGSRGPGRSRSQSRSQSQRPGQKRREEPR Predict reactive species Full Name: roundabout, axon guidance receptor, homolog 3 (Drosophila) Calculated Molecular Weight: 148 kDa Observed Molecular Weight: 200-250 kDa, 148 kDa GenBank Accession Number: BC008623 Gene Symbol: ROBO3 Gene ID (NCBI): 64221 RRID: AB_10643388 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q96MS0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.