Product Description
Size: 20ul / 150ul
The TSPAN6 (12293-1-AP) by Proteintech is a Polyclonal antibody targeting TSPAN6 in WB, ELISA applications with reactivity to human, mouse, rat samples
12293-1-AP targets TSPAN6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse colon tissue, rat colon tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
TSPAN6 (also known as TM4SF6) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN6 gene is widely expressed, with high mRNA levels in liver, pancreas, kidney, and ovary (PMID: 9782095). TSPAN6 has been reported as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner (PMID: 22908223).
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag2964 Product name: Recombinant human TSPAN6 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-245 aa of BC012389 Sequence: MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV Predict reactive species
Full Name: tetraspanin 6
Calculated Molecular Weight: 245 aa, 28 kDa
Observed Molecular Weight: 25-30 kDa
GenBank Accession Number: BC012389
Gene Symbol: TSPAN6
Gene ID (NCBI): 7105
RRID: AB_2213446
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: O43657
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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