Product Description
Size: 20ul / 150ul
The ASCC1 (12301-1-AP) by Proteintech is a Polyclonal antibody targeting ASCC1 in WB, ELISA applications with reactivity to human samples
12301-1-AP targets ASCC1 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HEK-293 cells, HeLa cells, Jurkat cells, Y79 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).
Specification
Tested Reactivity: human
Cited Reactivity: human
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag2946 Product name: Recombinant human ASCC1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-355 aa of BC012291 Sequence: MEVLRPQLIRIDGRNYRKNPVQEQTYQHEEDEEDFYQGSMECADEPCDAYEVEQTPQGFRSTLRAPSLLYKHIVGKRGDTRKKIEMETKTSISIPKPGQDGEIVITGQHRNGVISARTRIDVLLDTFRRKQPFTHFLAFFLNEVEVQEGFLRFQEEVLAKCSMDHGVDSSIFQNPKKLHLTIGMLVLLSEEEIQQTCEMLQQCKEEFINDISGGKPLEVEMAGIEYMNDDPGMVDVLYAKVHMKDGSNRLQELVDRVLERFQASGLIVKEWNSVKLHATVMNTLFRKDPNAEGRYNLYTAEGKYIFKERESFDGRNILKLFENFYFGSLKLNSIHISQRFTVDSFGNYASCGQID Predict reactive species
Full Name: activating signal cointegrator 1 complex subunit 1
Calculated Molecular Weight: 45.5 kDa
Observed Molecular Weight: 45.5 kDa
GenBank Accession Number: BC012291
Gene Symbol: ASCC1
Gene ID (NCBI): 51008
RRID: AB_2059350
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8N9N2
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
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