Product Description
Size: 20ul / 150ul
The TSPAN3 (13036-1-AP) by Proteintech is a Polyclonal antibody targeting TSPAN3 in IHC, IF/ICC, ELISA applications with reactivity to human, mouse samples
13036-1-AP targets TSPAN3 in IHC, IF/ICC, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive IHC detected in: mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF/ICC detected in: HeLa cells
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:50-1:500
Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500
Background Information
Tetraspanin-3 (TSPAN3, also known as TM4SF8) is a member of the tetraspanin (TM4SF) family. Tetraspanins, so named because they contain four transmembrane domains, are frequently expressed at the cell surface in association with each other and with other molecules, and they function to regulate cell adhesion, migration, proliferation, and differentiation. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair. TSPAN3 is a glycosylated protein and it is differentially glycosylated in different tissues (PMID: 27818272).
Specification
Tested Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag3689 Product name: Recombinant human TSPAN3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-253 aa of BC011206 Sequence: MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA Predict reactive species
Full Name: tetraspanin 3
Calculated Molecular Weight: 253 aa, 28 kDa
GenBank Accession Number: BC011206
Gene Symbol: TSPAN3
Gene ID (NCBI): 10099
RRID: AB_3085406
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: O60637
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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