Proteintech, 13707-1-AP, SEPT12 Polyclonal antibody

Size: 20ul / 150ul The SEPT12 (13707-1-AP) by Proteintech is a Polyclonal antibody targeting SEPT12 in WB, ELISA applications with reactivity to human, mouse, rat samples 13707-1-AP targets SEPT12 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, mouse testis tissue, rat brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information SEPT12, also known as Septin 12, SPGF10, is a member of the Septin GTPase family. The Septin family is a group of evolutionarily conserved GTP-binding proteins involved in various cellular processes. SEPT12 is a cytoskeletal GTPase that is specifically enriched in the testis. It plays a critical role in spermatogenesis, particularly in the formation and maintenance of sperm tail structures. Mutations or downregulation of SEPT12 have been linked to male infertility due to defects in sperm morphology and function(PMID: 30513371). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag4644 Product name: Recombinant human SEPT12 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-358 aa of BC035619 Sequence: MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWKSNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF Predict reactive species Full Name: septin 12 Calculated Molecular Weight: 358 aa, 41 kDa Observed Molecular Weight: 41 kDa GenBank Accession Number: BC035619 Gene Symbol: SEPT12 Gene ID (NCBI): 124404 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8IYM1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.