Proteintech, 13871-1-AP, KBTBD2 Polyclonal antibody

Size: 20ul / 150ul The KBTBD2 (13871-1-AP) by Proteintech is a Polyclonal antibody targeting KBTBD2 in WB, ELISA applications with reactivity to human, mouse, rat samples 13871-1-AP targets KBTBD2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: COLO 320 cells, A549 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information Kelch repeat and BTB domain containing 2(KBTBD2), also known as BTB and kelch domain-containing protein 1, encodes a BTB-Kelch family subunit that p85α-specific recognition for the Cullin3-based E3 ubiqitin ligase complex, which regulates p85α protein ubiquitination and subsequently regulates phosphoinositide-3 kinases (PI3K) signaling (PMID:27708159). However, the expression profile and functional significance of Kbtbd2 is still largely unknown. The Human Protein Atlas which is an online source shows high Kbtbd2 expression in the spleen and thymus, suggesting that Kbtbd2 might involved in immunization (PMID:29331106). In addition, Kbtbd2 is related to Src-induced phosphorylation of protein, spermatogonial stem cell activity(PMID:15623525, 29331106). A 60-70 kDa band has also been reported(PMID:27708159). Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag4823 Product name: Recombinant human KBTBD2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-349 aa of BC047107 Sequence: MSTQDERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQDAFMQLSHDLLIDILSSDNLNVGKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMRKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSRPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNC Predict reactive species Full Name: kelch repeat and BTB (POZ) domain containing 2 Calculated Molecular Weight: 622 aa, 71 kDa Observed Molecular Weight: 60-70 kDa GenBank Accession Number: BC047107 Gene Symbol: KBTBD2 Gene ID (NCBI): 25948 RRID: AB_2296330 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8IY47 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.