Product Description
Size: 20ul / 150ul
The DYNC2LI1 (15949-1-AP) by Proteintech is a Polyclonal antibody targeting DYNC2LI1 in WB, ELISA applications with reactivity to human, mouse samples
15949-1-AP targets DYNC2LI1 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HEK-293T cells, L02 cells, mouse brain tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
DYNC2LI1 (D2LIC, LIC3) is a member of cytoplasmic dynein 2 complex that is required for retrograde transport. It is ubiquitously expressed with high expression levels in brain, kidney, lung and testes. In mammalian cells, DYNC2LI1 is localized to centrosomal region Mutations in DYNC2LI1 disrupt cilia function and cause various skeletal ciliopathies. There're some isoforms with MW 40 kDa, 38 kDa, 22 kDa and 16 kDa.
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag8584 Product name: Recombinant human DYNC2LI1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-352 aa of BC006969 Sequence: MPSETLWEIAKAEVEKRGINGSEGDGAEIAEKFVFFIGSKNGGKTTIILRCLDRDEPPKPTLALEYTYGRRAKGHNTPKDIAHFWELGGGTSLLDLISIPITGDTLRTFSLVLVLDLSKPNDLWPTMENLLQATKSHVDKVIMKLGKTNAKAVSEMRQKIWNNMPKDHPQDHELIDPFPVPLVIIGSKYDVFQDFESEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFGIDKSKSICVDQNKPLFITAGLDSFGQIGSPPVPENDIGKLHAHSPMELWKKVYEKLFPPKSINTLKDIKDPARDPQYAENEVDEMRIQKDLELEQYKRSSSKSWKQIELDS Predict reactive species
Full Name: dynein, cytoplasmic 2, light intermediate chain 1
Calculated Molecular Weight: 352 aa, 40 kDa
Observed Molecular Weight: 37-40 kDa, 22 kDa
GenBank Accession Number: BC006969
Gene Symbol: DYNC2LI1
Gene ID (NCBI): 51626
RRID: AB_2093643
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8TCX1
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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