Proteintech, 17117-1-AP, KLHL11 Polyclonal antibody

Size: 20ul / 150ul The KLHL11 (17117-1-AP) by Proteintech is a Polyclonal antibody targeting KLHL11 in WB, ELISA applications with reactivity to human samples 17117-1-AP targets KLHL11 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: COLO 320 cells, MCF-7 cells Recommended dilution Western Blot (WB): WB : 1:200-1:1000 Background Information KLHL11 is a component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating ubiquitination of target proteins. The presence of antibodies directed against KLHL11 has been identified as biomarker of a paraneoplastic neurological syndrome. The downregulation of KLHL11 may contribute to the disease progression, owing to its putative function in protein quality control. The calculated molecular weight of KLHL11 is 80 kDa (PMID: 34312900). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag10805 Product name: Recombinant human KLHL11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 359-708 aa of BC034470 Sequence: DVIMVIGGVSEGGDYLSECVGYFVDEDRWVNLPHIHNHLDGHAVAVTESYVYVAGSMEPGFAKTVERYNPNLNTWEHVCSLMTRKHSFGLTEVKGKLYSIGGHGNFSPGFKDVTVYNPELDKWHNLESAPKILRDVKALAIEDRFVYIAARTPVDRDTEDGLKAVITCYDTETRQWQDVESLPLIDNYCFFQMSVVNSNFYQTASCCPKSYCLENEEAVRKIASQVSDEILESLPPEVLSIEGAAICYYKDDVFIIGGWKNSDDIDKQYRKEAYRYCAERKRWMLLPPMPQPRCRATACHVRIPYRYLHGTQRYPMPQNLMWQKDRIRQMQEIHRHALNMRRVPSSQIEC Predict reactive species Full Name: kelch-like 11 (Drosophila) Calculated Molecular Weight: 708 aa, 80 kDa Observed Molecular Weight: 80 kDa GenBank Accession Number: BC034470 Gene Symbol: KLHL11 Gene ID (NCBI): 55175 RRID: AB_2130733 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9NVR0 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.