Proteintech, 17970-1-AP, RGS9 Polyclonal antibody

Size: 20ul / 150ul The RGS9 (17970-1-AP) by Proteintech is a Polyclonal antibody targeting RGS9 in WB, ELISA applications with reactivity to human, mouse, rat samples 17970-1-AP targets RGS9 in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue, mouse eye tissue, SH-SY5Y cells, mouse retina tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:8000 Background Information RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS). Specification Tested Reactivity: human, mouse, rat Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag11976 Product name: Recombinant human RGS9 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 273-622 aa of BC022504 Sequence: SGENLGFWEACEDLKYGDQSKVKEKAEEIYKLFLAPGARRWINIDGKTMDITVKGLKHPHRYVLDAAQTHIYMLMKKDSYARYLKSPIYKDMLAKAIEPQETTKKSSTLPFMRRHLRSSPSPVILRQLEEEAKAREAANTVDITQPGQHMAPSPHLTVYTGTCMPPSPSSPFSSSCRSPRKPFASPSRFIRRPSTTICPSPIRVALESSSGLEQKGECSGSMAPRGPSVTESSEASLDTSWPRSRPRAPPKARMALSFSRFLRRGCLASPVFARLSPKCPAVSHGRVQPLGDVGQQLPRLKSKRVANFFQIKMDVPTGSGTCLMDSEDAGTGESGDRATEKEVICPWESL Predict reactive species Full Name: regulator of G-protein signaling 9 Calculated Molecular Weight: 622 aa, 71 kDa Observed Molecular Weight: 50-58 kDa, 70-75 kDa GenBank Accession Number: BC022504 Gene Symbol: RGS9 Gene ID (NCBI): 8787 RRID: AB_2178508 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O75916 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.