Proteintech, 18839-1-AP, SORCS1 Polyclonal antibody

Size: 20ul / 150ul The SORCS1 (18839-1-AP) by Proteintech is a Polyclonal antibody targeting SORCS1 in WB, ELISA applications with reactivity to human, mouse samples 18839-1-AP targets SORCS1 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: Y79 cells, HEK-293 cells, mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information SorCS1 is a 130 kDa type I transmembrane protein, belonging to Vps10p-domain (Vps10p-D) receptor family that comprises an N-terminal Vps10p-D, a leucine-rich domain, a single transmembrane domain, and a short cytoplasmic domain. SorCS1 is synthesized as a proprotein, which is converted to the mature receptor in late Golgi compartments by cleavage of the N-terminal propeptide. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic domains and differential expression in tissues. This antibody was generated against the C-terminal region of human SorCS1 and recognizes various forms of SorCS1. Multiple bands around 100-130 kDa as well as 60-80 kDa have been detected in Y79 cells by western blot assay. Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: sortilin-related VPS10 domain containing receptor 1 Calculated Molecular Weight: 1168 aa, 130 kDa Observed Molecular Weight: 130 kDa, 60-80 kDa GenBank Accession Number: BC131597 Gene Symbol: SORCS1 Gene ID (NCBI): 114815 RRID: AB_2878564 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q8WY21 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.