Proteintech, 18842-1-AP, LPPR5 Polyclonal antibody

Size: 20ul / 150ul The LPPR5 (18842-1-AP) by Proteintech is a Polyclonal antibody targeting LPPR5 in IHC, ELISA applications with reactivity to human, mouse samples 18842-1-AP targets LPPR5 in IHC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information The lipid phosphate phosphatase-related proteins (LPPRs), also known as plasticity-related genes (PRGs), are a family of six transmembrane proteins that are enriched in brain. To date, five members have been identified (LPPR1-LPPR5). LPPR5 is an integral membrane protein linked to neuronal plasticity, which impedes NogoA- and LPA-mediated RhoA kinase signaling. LPPR5 modulates the Rho-GTPase pathway involved in cancer growth, vascularization, and the adaptive response to changes in the microenvironment. LPPR5 is pivotal in influencing growth, angiogenesis, and therapeutic resistance. (PMID: 26183180, PMID: 35328529) Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: phosphatidic acid phosphatase type 2 Calculated Molecular Weight: 35 kDa GenBank Accession Number: NM_001010861 Gene Symbol: PAP2D Gene ID (NCBI): 163404 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q32ZL2 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.