Product Description
Size: 20ul / 150ul
The HOXB9 (18894-1-AP) by Proteintech is a Polyclonal antibody targeting HOXB9 in WB, ELISA applications with reactivity to human, mouse, rat samples
18894-1-AP targets HOXB9 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: K-562 cells, HT-29 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
HOXB9 is a member of the Homeobox (HOX) gene family, which plays a crucial role in embryonic development and is involved in the regulation of gene expression during this process. In addition to its role in embryogenesis, HOXB9 has been implicated in various cancers, including breast and prostate cancer. It is overexpressed in breast cancer tissue and is regulated by estrogen, playing a critical role in angiogenesis. HOXB9 overexpression has been shown to stimulate three-dimensional colony formation in soft-agar assays, indicating its role in tumorigenesis. Furthermore, HOXB9 binds to the promoters of various tumor growth and angiogenic factors, regulating their expression, and its homeodomain plays a crucial role in transcriptional regulation and tumorigenesis.
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag13502 Product name: Recombinant human HOXB9 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-202 aa of BC015565 Sequence: MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEK Predict reactive species
Full Name: homeobox B9
Calculated Molecular Weight: 250 aa, 28 kDa
Observed Molecular Weight: 30-32 kDa
GenBank Accession Number: BC015565
Gene Symbol: HOXB9
Gene ID (NCBI): 3219
RRID: AB_3085571
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P17482
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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