Proteintech, 20046-1-AP, MED13L Polyclonal antibody

Size: 20ul / 150ul The MED13L (20046-1-AP) by Proteintech is a Polyclonal antibody targeting MED13L in WB, ELISA applications with reactivity to human samples 20046-1-AP targets MED13L in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: K-562 cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information MED13L, also named as KIAA1025, PROSIT240, THRAP2 and TRAP240L, belongs to the Mediator complex subunit 13 family. It is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED13L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED13L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. The antibody has no cross reaction to MED13. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: mediator complex subunit 13-like Calculated Molecular Weight: 243 kDa Observed Molecular Weight: 240 kDa GenBank Accession Number: NM_015335 Gene Symbol: MED13L Gene ID (NCBI): 23389 RRID: AB_3085597 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q71F56 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.