Proteintech, 20548-1-AP, ERCC6/CSB Polyclonal antibody

Size: 20ul / 150ul The ERCC6/CSB (20548-1-AP) by Proteintech is a Polyclonal antibody targeting ERCC6/CSB in WB, ELISA applications with reactivity to human, mouse, rat samples 20548-1-AP targets ERCC6/CSB in WB, ELISA applications and shows reactivity with human, mouse, rat samples. Tested Applications Positive WB detected in: mouse brain tissue Recommended dilution Western Blot (WB): WB : 1:200-1:1000 Background Information ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6. Specification Tested Reactivity: human, mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: excision repair cross-complementing rodent repair deficiency, complementation group 6 Calculated Molecular Weight: 168 kDa Observed Molecular Weight: 150 kDa GenBank Accession Number: NM_000124 Gene Symbol: ERCC6/CSB Gene ID (NCBI): 2074 RRID: AB_10732961 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q03468 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.