Proteintech, 20690-1-AP, NRG2 Polyclonal antibody

Size: 20ul / 150ul The NRG2 (20690-1-AP) by Proteintech is a Polyclonal antibody targeting NRG2 in WB, IHC, ELISA applications with reactivity to human samples 20690-1-AP targets NRG2 in WB, IHC, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: U-251 cells, U-87 MG cells, fetal human brain tissue Positive IHC detected in: human gliomas tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunohistochemistry (IHC): IHC : 1:50-1:500 Background Information NRG2 is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: neuregulin 2 Calculated Molecular Weight: 92 kDa Observed Molecular Weight: 46 kDa GenBank Accession Number: NM_004883 Gene Symbol: NRG2 Gene ID (NCBI): 9542 RRID: AB_3085611 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O14511 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.